AFM studies of DNA condensation


Model


AFM images

Toroidal DNA-surfactant complexes on mica substrate. AFM study.
 


 

DNA molecules condensed in water-isopropanol media and deposited onto mica substrate. AFM study.


We carried out the set of AFM-studies of different DNA-condensation mechanisms in media with different polarity (aqueous solution, water-alcohol mixture, chloroform and so on). The most interesting results may be found:

1. V.G. Sergeyev, O.A. Pyshkina, M.O. Gallyamov, I.V. Yaminsky, A.B. Zezin, V.A.Kabanov, DNA-surfactant complexes in organic media. // Progr Colloid Polym Sci. 1997, v. 106, pp. 198–203.

2. M.O Gallyamov, O.A. Pyshkina, V.G. Sergeyev, I.V. Yaminsky, Scanning probe microscopy study of DNA conformational properties // Surface investigation: X-ray, synchrotron and neutron techniques. 1998, v. 14, No 2, pp. 247–251.

For more information see also.

 Joint SPM group

Nucleic acids researches